Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927067 | 0.89 | MAPT (0.44) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL30258055 | 0.89 | MAPT (0.44) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL13832477 | 0.89 | MAPT (0.40) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL29437965 | 0.87 | MAPT (0.39) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL15308385 | 0.87 | MAPT (0.39) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL19749963 | 0.87 | MAPT (0.39) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL21980924 | 0.82 | SUV39H2 (0.42) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL13832421 | 0.82 | SUV39H2 (0.42) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL1978678 | 0.82 | MAPT (0.42) | MAPTGAAMAPK1L3MBTL1TDP1 | |
| SCHEMBL1980442 | 0.82 | MAPT (0.42) | MAPTGAAMAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |