Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17206686 | 0.91 | MCHR1 (0.48) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL9924252 | 0.90 | PDE4B (0.42) | MCHR1KDM4EGAAADRA2AADRA1A | |
| SCHEMBL17206701 | 0.84 | MCHR1 (0.44) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL9924422 | 0.84 | KCNQ3 (0.42) | MCHR1KDM4EADRA2AADRA1AHRH1 | |
| SCHEMBL9924233 | 0.84 | KMT2A (0.49) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL9900854 | 0.83 | KCNQ3 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL9901952 | 0.83 | KCNQ3 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL17206691 | 0.83 | KCNQ3 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL9900852 | 0.83 | KCNQ3 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL9924234 | 0.83 | EPHX2 (0.41) | MCHR1ADRA2AADRA1AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |