Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400853 | 0.88 | MKNK1 (0.58) | MKNK1MKNK2DEGS1NPC1LMNA | |
| SCHEMBL403130 | 0.88 | MKNK1 (0.58) | MKNK1MKNK2DEGS1NPC1LMNA | |
| SCHEMBL13267488 | 0.80 | MKNK1 (0.56) | MKNK1MKNK2HDAC6SMPD1DEGS1 | |
| SCHEMBL13659688 | 0.79 | ADRB3 (0.42) | LMNANAMPT | |
| SCHEMBL12320670 | 0.76 | — | — | |
| SCHEMBL12320741 | 0.76 | — | — | |
| SCHEMBL404445 | 0.75 | HDAC1 (0.46) | — | |
| SCHEMBL404297 | 0.74 | — | — | |
| SCHEMBL10285924 | 0.74 | HDAC1 (0.52) | LMNA | |
| SCHEMBL13267214 | 0.74 | HDAC1 (0.58) | MKNK2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618087-B1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2012-06-13 | — | — | EP | disclosed |