Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269755 | 1.00 | USP2 (0.67) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL4883455 | 0.94 | USP2 (0.68) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL4849321 | 0.94 | USP2 (0.68) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL9926073 | 0.94 | USP2 (0.68) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL13987651 | 0.94 | USP2 (0.68) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL9925996 | 0.93 | USP2 (0.70) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL13987636 | 0.91 | USP2 (0.64) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL9926011 | 0.91 | USP2 (0.68) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL14269757 | 0.91 | USP2 (0.68) | USP2MAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL9926072 | 0.90 | USP2 (0.71) | USP2MAPTSMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836180-B1 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | SANOFI SA (FR) | 2012-06-13 | — | — | EP | disclosed |
| US-7468369-B2 | Sulfonyl pyrrolidines, method for producing the same and their use as drugs | SANOFI-AVENTIS (FR) | 2008-12-23 | — | — | US | disclosed |
| US-7468369-B2 | Sulfonyl pyrrolidines, method for producing the same and their use as drugs | SANOFI-AVENTIS (FR) | 2008-12-23 | — | — | US | disclosed |