SCHEMBL9926151

SCHEMBL9926151

c1cc(-c2ccc(-c3ccc4c(c3)c3cccc5c3n4-c3ccccc3O5)cc2)cc(-c2cccc(-c3ccc4c(c3)c3cccc5c3n4-c3ccccc3O5)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.34
PDE4B Q07343 1/20 0.33
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
PLA2G10 O15496 1/20 0.33
P2RX4 Q99571 4/20 0.33
TSPO P30536 1/20 0.32
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
DNM1 Q05193 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
MEN1 O00255 1/20 0.30
ESR1 P03372 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9926149 1.00 PRKDC (0.34) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL9926144 1.00 PRKDC (0.34) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL9926145 1.00 PRKDC (0.34) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL20976227 0.99 PRKDC (0.36) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL20976228 0.99 PRKDC (0.36) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL20976188 0.99 PRKDC (0.36) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL9926148 0.99 PDE4B (0.34) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL9926180 0.99 PDE4B (0.34) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL9926141 0.99 PDE4B (0.34) PRKDCPDE4BPLA2G2APLA2G4APLA2G10
SCHEMBL9926139 0.97 PRKDC (0.35) PRKDCPDE4BPLA2G2APLA2G4APLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2649080-B1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KK (JP) 2018-04-04 EP disclosed
US-9515270-B2 Indolophenoxazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2016-12-06 US disclosed
US-9515270-B2 Indolophenoxazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2016-12-06 US disclosed
US-20130228770-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-09-05 US disclosed
US-20130228770-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-09-05 US disclosed
WO-2012077582-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-06-14 WO disclosed