Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 10/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 10/20 | 1.00 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.85 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35212190 | 0.92 | TNKS2 (1.00) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9904845 | 0.92 | TNKS2 (1.00) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL29372843 | 0.92 | TNKS2 (1.00) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9904844 | 0.92 | TNKS2 (1.00) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL23772382 | 0.84 | TNKS (0.86) | TNKSTNKS2SULT2A1HPGDSMN1; SMN2 | |
| SCHEMBL9905155 | 0.84 | TNKS (0.86) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9905154 | 0.84 | TNKS (0.86) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL15449894 | 0.83 | TNKS (0.84) | TNKSTNKS2SULT2A1HPGDSMN1; SMN2 | |
| SCHEMBL9926210 | 0.81 | TNKS2 (0.81) | TNKSTNKS2SULT2A1PIM1PIM2 | |
| SCHEMBL15449840 | 0.81 | TNKS (0.74) | TNKSTNKS2SULT2A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076898-A1 | TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-06-14 | — | — | WO | disclosed |