Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30518015 | 1.00 | KDR (0.47) | KDRALDH1A1HPGDAKT1MMP13 | |
| SCHEMBL3786661 | 0.87 | HDAC8 (0.50) | KDRALDH1A1HPGDHDAC8HDAC6 | |
| SCHEMBL1003995 | 0.87 | TPMT (0.52) | KDRALDH1A1HPGDHDAC8HDAC6 | |
| SCHEMBL1003295 | 0.85 | TPMT (0.54) | ALDH1A1HPGDMMP13HDAC8HDAC6 | |
| SCHEMBL15492141 | 0.85 | HDAC8 (0.52) | ALDH1A1HPGDMMP13HDAC8HDAC6 | |
| SCHEMBL13485819 | 0.84 | HDAC6 (0.53) | KDRAKT1KCNK3KCNK9HDAC8 | |
| SCHEMBL14060074 | 0.83 | TPMT (0.48) | KDRALDH1A1HPGDHDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL21438790 | 0.83 | TPMT (0.52) | ALDH1A1HPGDMMP13HDAC8HDAC6 | |
| SCHEMBL17809693 | 0.79 | GRN (0.50) | KDRHPGDGRNSORT1 | |
| SCHEMBL3487410 | 0.79 | PLK1 (0.42) | ALDH1A1HPGDHDAC8HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684108-A | Method for catalyzing coupling reaction of aryl halide and carbon monoxide by using composite catalyst | 浙江予睿化学科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | NOVARTIS AG (CH) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149661-A1 | TETRA-SUBSTITUTED HETEROARYL COMPOUNDS AND THEIR USE AS MDM2 AND/OR MDM4 MODULATORS | MDM4, MDM2, TP53 | KDR 2373/4885ALDH1A1 4361/4885HPGD 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.