Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23662320 | 0.86 | CA12 (0.47) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL2884545 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL158111 | 0.82 | TDP1 (0.57) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL45823 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL8109850 | 0.81 | CA12 (0.46) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12534230 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL24539560 | 0.81 | CA1 (0.46) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12874079 | 0.80 | CA12 (0.69) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL131661 | 0.80 | CA12 (0.69) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL30409057 | 0.80 | TDP1 (0.55) | KDM4EALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463279-A1 | AMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011016469-A1 | AMIDE DERIVATIVE | 第一三共株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |
| WO-2010065760-A1 | IMIDAZO [1,2A] PYRIDINE DERIVATIVES, THEIR USE AS S1P1 AGONISTS AND METHODS FOR THEIR PRODUCTION | EXELIXIS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009050523-A1 | AZETIDINYL G-PROTEIN COUPLED RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050522-A1 | AZETIDINYL G-PROTEIN COUPLED RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |