Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377430 | 0.86 | CYP2D6 (0.50) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| SCHEMBL1785409 | 0.86 | MAPK1 (0.65) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| SCHEMBL263461 | 0.83 | TDP1 (0.58) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| SCHEMBL444728 | 0.81 | CYP2D6 (0.61) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| SCHEMBL5085501 | 0.81 | CYP2D6 (0.53) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| Hydrogen Peroxide SCHEMBL28730771 | 0.81 | CYP2D6 (0.61) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| SCHEMBL2804706 | 0.80 | CYP2D6 (0.51) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| Water SCHEMBL5946543 | 0.80 | CYP2D6 (0.59) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| SCHEMBL726575 | 0.80 | CYP2D6 (0.51) | TSHRCYP2D6MAPK1HIF1ACYP1A2 | |
| SCHEMBL11637934 | 0.80 | CYP2D6 (0.51) | TSHRCYP2D6MAPK1HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434796-B2 | Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same | W. R. GRACE & CO.-CONN. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9434796-B2 | Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same | W. R. GRACE & CO.-CONN. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9434796-B2 | Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same | W. R. GRACE & CO.-CONN. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9382342-B2 | Procatalyst composition with alkoxyalkyl 2-propenoate internal electron donor and polymer from same | W. R. GRACE & CO.-CONN. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9315592-B2 | Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product | W. R. GRACE & CO.-CONN. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315592-B2 | Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product | W. R. GRACE & CO.-CONN. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315592-B2 | Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product | W. R. GRACE & CO.-CONN. (US) | 2016-04-19 | — | — | US | disclosed |
| EP-2655435-B1 | PROCATALYST COMPOSITION WITH ALKOXYALKYL 2-PROPENOATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | GRACE W R & CO (US) | 2015-09-23 | — | — | EP | disclosed |
| US-20140046009-A1 | Procatalyst Composition with Alkoxyalkyl 2-Propenoate Internal Electron Donor and Polymer from Same | W. R. GRACE & CO.-CONN. | 2014-02-13 | — | — | US | disclosed |
| US-8604146-B2 | Catalyst composition with alkoxyalkyl ester internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| WO-2012087527-A1 | PROCESS FOR PRODUCING PROCATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND PRODUCT | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087536-A1 | PROCATALYST COMPOSITION WITH ALKOXYALKYL 2-PROPENOATE INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087531-A1 | CATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND POLYMER FROM SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120157642-A1 | Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same | W.R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157643-A1 | Procatalyst Composition with Alkoxyalkyl 2-Propenoate Internal Electron Donor and Polymer from Same | W.R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157642-A1 | Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same | W.R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157295-A1 | Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product | W. R. GRACE & CO. - CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157295-A1 | Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product | W. R. GRACE & CO. - CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157642-A1 | Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same | W.R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |
| US-20120157295-A1 | Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product | W. R. GRACE & CO. - CONN. | 2012-06-21 | — | — | US | disclosed |