Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931550 | 1.00 | PEPD (0.31) | PEPDSTAT6MEN1KMT2A | |
| SCHEMBL9931548 | 1.00 | PEPD (0.31) | PEPDSTAT6MEN1KMT2A | |
| SCHEMBL9931549 | 1.00 | PEPD (0.31) | PEPDSTAT6MEN1KMT2A | |
| SCHEMBL9931310 | 0.97 | PEPD (0.32) | PEPDSTAT6MEN1KMT2A | |
| SCHEMBL9931312 | 0.97 | PEPD (0.32) | PEPDSTAT6MEN1KMT2A | |
| SCHEMBL9931313 | 0.97 | PEPD (0.32) | PEPDSTAT6MEN1KMT2A | |
| SCHEMBL9972607 | 0.83 | HSD17B10 (0.37) | MEN1KMT2A | |
| SCHEMBL9972620 | 0.81 | HSD17B10 (0.38) | MEN1KMT2A | |
| SCHEMBL9931264 | 0.73 | POLB (0.36) | PEPDMEN1KMT2A | |
| SCHEMBL9931266 | 0.73 | POLB (0.36) | PEPDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157421-A1 | 17Beta-Alkyl-17Alpha-oxy-estratrienes | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157421-A1 | 17Beta-Alkyl-17Alpha-oxy-estratrienes | CYP19A1, HSD17B11, CYP17A1 | PEPD 1220/4885STAT6 4862/4885MEN1 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.