Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.58 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130416 | 0.94 | HTR2C (0.64) | HTR2CPTGS2PTGDR2HTR2AHTR2B | |
| SCHEMBL1128179 | 0.94 | HTR2C (0.64) | HTR2CPTGS2PTGDR2HTR2AHTR2B | |
| SCHEMBL29871435 | 0.94 | HTR2C (0.64) | HTR2CPTGS2PTGDR2HTR2AHTR2B | |
| SCHEMBL31469392 | 0.92 | HTR2C (0.67) | HTR2CPTGS2PTGDR2HTR2AHTR2B | |
| SCHEMBL43079 | 0.92 | HTR2C (0.67) | HTR2CPTGS2PTGDR2HTR2AHTR2B | |
| Hydrogen Peroxide SCHEMBL9938282 | 0.88 | HTR2C (0.62) | HTR2CPTGS2PTGDR2NPC1RAB9A | |
| SCHEMBL1515219 | 0.87 | HTR2C (0.67) | HTR2CHTR2AHTR2BDDB1CRBN | |
| SCHEMBL1225741 | 0.83 | HTR2C (0.72) | HTR2CHTR2AHTR2BDDB1CRBN | |
| SCHEMBL18600336 | 0.82 | HTR2C (0.71) | HTR2C | |
| SCHEMBL10621727 | 0.81 | HTR2C (0.55) | HTR2CPTGS2PTGDR2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082232-A1 | PROCESS FOR PRODUCING CYCLOALKYLAROMATIC COMPOUNDS | EXXONMOBIL CHEMICAL PATENST INC. (US) | 2012-06-21 | — | — | WO | disclosed |