Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938751 | 0.91 | MME (0.87) | MMEACE | |
| SCHEMBL15464488 | 0.91 | MME (0.87) | MMEACE | |
| SCHEMBL15464367 | 0.90 | MME (0.61) | MMEACE | |
| Trifluoroacetic Acid SCHEMBL29582786 | 0.88 | MME (0.59) | MMEACE | |
| SCHEMBL9929651 | 0.87 | MME (0.62) | MMEACE | |
| SCHEMBL15464238 | 0.87 | MME (0.88) | MMEACE | |
| SCHEMBL9937367 | 0.87 | MME (0.88) | MMEACE | |
| SCHEMBL9929822 | 0.86 | MME (0.78) | MMEACE | |
| SCHEMBL9937317 | 0.85 | MME (0.77) | MMEACE | |
| SCHEMBL15464366 | 0.85 | MME (0.77) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651896-A1 | NEPRILYSIN INHIBITORS | Theravance, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082853-A1 | NEPRILYSIN INHIBITORS | THERAVANCE, INC. (US) | 2012-06-21 | — | — | WO | disclosed |