Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15464151 | 1.00 | MME (0.71) | MMEACE | |
| SCHEMBL15464087 | 0.93 | MME (0.69) | MMEACE | |
| SCHEMBL15464367 | 0.92 | MME (0.61) | MMEACE | |
| SCHEMBL15463747 | 0.91 | MME (0.72) | MMEACE | |
| SCHEMBL9938751 | 0.91 | MME (0.87) | MMEACE | |
| SCHEMBL15464488 | 0.91 | MME (0.87) | MMEACE | |
| SCHEMBL15464388 | 0.88 | MME (0.62) | MMEACE | |
| Trifluoroacetic Acid SCHEMBL29582786 | 0.87 | MME (0.59) | MMEACE | |
| Trifluoroacetic Acid SCHEMBL29583330 | 0.85 | MME (0.59) | MMEACE | |
| SCHEMBL9939120 | 0.85 | MME (0.63) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651896-A1 | NEPRILYSIN INHIBITORS | Theravance, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082853-A1 | NEPRILYSIN INHIBITORS | THERAVANCE, INC. (US) | 2012-06-21 | — | — | WO | disclosed |