Sulfosulfuron

Sulfosulfuron

SCHEMBL9938892

CCS(=O)(=O)c1nc2ccccn2c1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1.COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2cc(CNS(C)(=O)=O)ccc2C(=O)O)n1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.39
GAA P10253 1/20 0.37
MAPT P10636 2/20 0.36
TP53 P04637 1/20 0.36
GLA P06280 1/20 0.36
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
NPC1 O15118 1/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
LMNA P02545 1/20 0.30
PKM P14618 1/20 0.30
HTT P42858 1/20 0.30
HDAC1 Q13547 1/20 0.30
FABP4 P15090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfosulfuron SCHEMBL66574 0.85 GAA (0.49) CDK1GAAMAPTTP53GLA
SCHEMBL121017 0.84 CDK1 (0.52) CDK1GAAMAPTTP53GLA
SCHEMBL13370005 0.84 CDK1 (0.52) CDK1GAAMAPTTP53GLA
Sulfosulfuron SCHEMBL8476425 0.83 GAA (0.46) CDK1GAAMAPTTP53GLA
SCHEMBL21585569 0.83 CDK1 (0.51) CDK1GAAMAPTTP53GLA
SCHEMBL6443045 0.81 CDK1 (0.49) CDK1GAAMAPTTP53GLA
SCHEMBL15273260 0.79 CDK1 (0.46) CDK1GAAMAPTTP53GLA
SCHEMBL19463933 0.78 CDK1 (0.50) CDK1GAAMAPTTP53GLA
Metam SCHEMBL2583507 0.78 CDK1 (0.46) CDK1GAAMAPTTP53GLA
SCHEMBL19283719 0.78 CDK1 (0.52) CDK1GAAMAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053514-B2 Soybean event SYHT0H2 and compositions and methods for detection thereof SYNGENTA PARTICIPATIONS AG (CH) 2021-07-06 US disclosed
US-20190078115-A1 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2019-03-14 US disclosed
US-10184134-B2 Soybean event SYHT0H2 and compositions and methods for detection thereof SYNGENTA PARTICIPATIONS AG (CH) 2019-01-22 US disclosed
US-10006044-B2 Soybean event SYHT04R and compositions and methods for detection thereof SYNGENTA PARTICIPATIONS AG (CH) 2018-06-26 US disclosed
US-20140310835-A1 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2014-10-16 US disclosed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO disclosed