Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13771769 | 0.86 | KMT2A (0.48) | KMT2AMAPK1HSD11B1ALDH1A1CYP2C9 | |
| SCHEMBL4748013 | 0.86 | KMT2A (0.48) | KMT2AMAPK1HSD11B1ALDH1A1CYP2C9 | |
| SCHEMBL13770629 | 0.86 | KMT2A (0.48) | KMT2AMAPK1HSD11B1ALDH1A1CYP2C9 | |
| SCHEMBL14310833 | 0.78 | KMT2A (0.41) | KMT2AALDH1A1CHRM2CHRM4CHRM5 | |
| SCHEMBL739505 | 0.78 | KMT2A (0.71) | KMT2AMAPK1HPGD | |
| SCHEMBL14310707 | 0.78 | KMT2A (0.71) | KMT2AMAPK1HPGD | |
| SCHEMBL9428951 | 0.78 | KMT2A (0.71) | KMT2AMAPK1HPGD | |
| SCHEMBL4791304 | 0.78 | KMT2A (0.43) | KMT2AMAPK1 | |
| SCHEMBL10514993 | 0.76 | KMT2A (0.52) | KMT2AMAPK1HSD11B1ALDH1A1HPGD | |
| SCHEMBL4748087 | 0.73 | KMT2A (0.48) | KMT2AMAPK1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463274-A1 | Tri-or tetra-substituted-3-aminopyrrolidine deritatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-06-13 | — | — | EP | disclosed |