Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 3/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448208 | 0.85 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL5493306 | 0.84 | CYP1B1 (0.42) | CYP19A1SHBG | |
| SCHEMBL27746078 | 0.83 | CYP19A1 (0.40) | CYP19A1SHBGSERPINA6MEN1LMNA | |
| SCHEMBL4152712 | 0.82 | ESR1 (0.45) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL3112585 | 0.82 | ESR1 (0.45) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL3112594 | 0.82 | ESR1 (0.45) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL5308406 | 0.82 | CYP19A1 (0.42) | CYP19A1L3MBTL1SHBGSERPINA6ESR1 | |
| SCHEMBL7475323 | 0.80 | TDP1 (0.44) | CYP19A1MEN1CYP3A4KMT2A | |
| SCHEMBL28188365 | 0.80 | CYP19A1 (0.44) | CYP19A1L3MBTL1SHBGSERPINA6ESR1 | |
| SCHEMBL20537122 | 0.80 | CYP19A1 (0.47) | CYP19A1L3MBTL1SHBGSERPINA6ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501374-B | A method of recycling dehydroepiandros-sterone from dehydroepiandros-sterone mother liquor object | 湖北竹溪人福药业有限责任公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-106565807-B | A kind of separation DHEA and its αisomer method | 湖北竹溪人福药业有限责任公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-107501374-A | A kind of method that dehydroepiandros-sterone is reclaimed in the mother liquor thing from dehydroepiandros-sterone | 湖北竹溪人福药业有限责任公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-106565807-A | Method for separating DHEA and alpha-isomers thereof | 湖北竹溪人福药业有限责任公司 | 2017-04-19 | — | — | CN | disclosed |
| WO-2014137420-A1 | RECEPTOR AND KINASE MODULATOR SCREENING METHODS | Harbor Therapeutics, Inc. (US) | 2014-09-12 | — | — | WO | disclosed |
| EP-2667876-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | Harbor BioSciences, Inc. (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012083090-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | HARBOR BIOSCIENCES, INC. (US) | 2012-06-21 | — | — | WO | disclosed |