Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 7/20 | 0.79 |
| ▸ | ATP1B1 | P05026 | 7/20 | 0.79 |
| ▸ | ATP1A3 | P13637 | 7/20 | 0.79 |
| ▸ | ATP1B2 | P14415 | 7/20 | 0.79 |
| ▸ | ATP1A2 | P50993 | 7/20 | 0.79 |
| ▸ | ATP1B3 | P54709 | 7/20 | 0.79 |
| ▸ | FXYD2 | P54710 | 7/20 | 0.79 |
| ▸ | ATP1A4 | Q13733 | 7/20 | 0.79 |
| ▸ | TP53 | P04637 | 6/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | RAB9A | P51151 | 3/20 | 0.79 |
| ▸ | NPC1 | O15118 | 2/20 | 0.79 |
| ▸ | STAT3 | P40763 | 2/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | SLCO4C1 | Q6ZQN7 | 1/20 | 0.79 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gitoxin SCHEMBL25639501 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL29691433 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL30883086 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL18947800 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL18364705 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL12556684 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL14648721 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL309847 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL20582695 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Gitoxin SCHEMBL27272378 | 0.97 | TP53 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082771-A1 | CARDIAC GLYCOSIDES FOR TREATING AUTOIMMUNE DISEASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-06-21 | — | — | WO | disclosed |