Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800623 | 0.99 | ESR1 (0.49) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491267 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491344 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491223 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491210 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491218 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491288 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491280 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491242 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 | |
| SCHEMBL17491293 | 0.94 | ESR1 (0.52) | ESR1DGKAALDH1A1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652014-A2 | PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING | Cytec Technology Corp. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082578-A2 | PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING | CYTEC TECHNOLOGY CORP. (US) | 2012-06-21 | — | — | WO | disclosed |