Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302695 | 0.91 | CYP3A4 (0.64) | CYP3A4TNKSCYP2D6 | |
| SCHEMBL18053807 | 0.90 | CYP3A4 (0.49) | CYP3A4TNKSCYP2D6 | |
| SCHEMBL15306467 | 0.89 | CYP3A4 (0.40) | CYP3A4 | |
| SCHEMBL18056538 | 0.88 | CYP3A4 (0.49) | CYP3A4TNKSCYP2D6 | |
| SCHEMBL18053793 | 0.88 | CYP3A4 (0.51) | CYP3A4TNKSCYP2D6 | |
| SCHEMBL18056536 | 0.87 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL18053802 | 0.86 | CYP3A4 (0.38) | CYP3A4 | |
| SCHEMBL18056523 | 0.86 | CYP3A4 (0.54) | CYP3A4TNKSCYP2D6 | |
| SCHEMBL18056535 | 0.86 | CYP3A4 (0.47) | CYP3A4TNKSCYP2D6 | |
| SCHEMBL9940791 | 0.86 | CYP3A4 (0.49) | CYP3A4TNKSCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896459-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-20 | — | — | US | disclosed |
| US-9896459-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-20 | — | — | US | disclosed |
| US-9896459-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-20 | — | — | US | disclosed |
| EP-2651936-B1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-02-22 | — | — | EP | disclosed |
| EP-2651936-B1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-02-22 | — | — | EP | disclosed |
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-09-01 | — | — | US | disclosed |
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-09-01 | — | — | US | disclosed |
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-09-01 | — | — | US | disclosed |
| US-9339494-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IR) | 2016-05-17 | — | — | US | disclosed |
| US-9339494-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IR) | 2016-05-17 | — | — | US | disclosed |
| US-20150231119-A1 | Azaindoles As Respiratory Syncytial Virus Antiviral Agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-08-20 | — | — | US | disclosed |
| US-9051317-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-06-09 | — | — | US | disclosed |
| US-9051317-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-06-09 | — | — | US | disclosed |
| US-9051317-B2 | Azaindoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2015-06-09 | — | — | US | disclosed |
| EP-2651936-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | Janssen R&D Ireland (IE) | 2013-10-23 | — | — | EP | disclosed |
| US-20130267556-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| US-20130267556-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| US-20130267556-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| WO-2012080450-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080450-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150231119-A1 | Azaindoles As Respiratory Syncytial Virus Antiviral Agents | AZI2, CCNI, ZC3HAV1 | CYP3A4 514/4885TNKS 1704/4885CYP2D6 1484/4885 |
| US-20160251377-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | AZI2, CCNI, ZC3HAV1 | CYP3A4 514/4885TNKS 1704/4885CYP2D6 1484/4885 |
| US-20130267556-A1 | AZAINDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | AZI2, CCNI, ZC3HAV1 | CYP3A4 514/4885TNKS 1704/4885CYP2D6 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.