Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942138 | 1.00 | CHRM3 (0.48) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12099347 | 0.87 | CHRM3 (0.56) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4887549 | 0.80 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4891590 | 0.80 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL15117578 | 0.80 | CHRM3 (0.55) | CHRM3CHRM2CHRM1 | |
| SCHEMBL14015868 | 0.78 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9967808 | 0.78 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4893085 | 0.77 | CHRM3 (0.48) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4897583 | 0.77 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9940056 | 0.76 | CHRM3 (0.49) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146957-B1 | QUATERNARY AMMONIUM COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE INC (US) | 2013-06-12 | — | — | EP | disclosed |
| US-8202891-B2 | Quaternary ammonium compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2012-06-19 | — | — | US | disclosed |