Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9942206 | 0.93 | TTK (0.51) | TTKCAMKK2 | |
| SCHEMBL9942176 | 0.91 | TTK (0.51) | TTKCAMKK2 | |
| SCHEMBL9942746 | 0.90 | TTK (0.52) | TTK | |
| SCHEMBL9942170 | 0.90 | TTK (0.54) | TTKCAMKK2 | |
| SCHEMBL9942689 | 0.89 | TTK (0.53) | TTK | |
| SCHEMBL9942337 | 0.89 | TTK (0.48) | TTKCAMKK2 | |
| SCHEMBL9942692 | 0.88 | TTK (0.52) | TTK | |
| SCHEMBL9942208 | 0.88 | TTK (0.56) | TTK | |
| SCHEMBL9940276 | 0.87 | TTK (0.55) | TTK | |
| SCHEMBL9942701 | 0.86 | TTK (0.51) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651950-A1 | 6 SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Bayer Intellectual Property GmbH (DE) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080230-A1 | 6 SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-21 | — | — | WO | claimed |