Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 7/20 | 0.32 |
| ▸ | JAK3 | P52333 | 7/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.32 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628870 | 0.84 | NR4A2 (0.36) | NR4A2JAK2JAK3MAP3K7TAB1 | |
| SCHEMBL9942576 | 0.84 | NR4A2 (0.35) | NR4A2MAP3K7TAB1CYP2C9 | |
| SCHEMBL2628871 | 0.83 | NR4A2 (0.35) | NR4A2JAK2JAK3MAP3K7TAB1 | |
| SCHEMBL1763549 | 0.83 | NR4A2 (0.35) | NR4A2JAK2JAK3MAP3K7TAB1 | |
| SCHEMBL1762967 | 0.83 | CYP2C9 (0.43) | ALDH1A1NR4A2MEN1KMT2ACYP2C9 | |
| SCHEMBL7063069 | 0.77 | CYP2C9 (0.41) | ALDH1A1LMNAJAK2JAK3MEN1 | |
| SCHEMBL1763185 | 0.72 | NR4A2 (0.45) | ALDH1A1NR4A2LMNAHTT | |
| SCHEMBL12215466 | 0.71 | CYP2C9 (0.44) | ALDH1A1NR4A2MEN1KMT2ACYP2C9 | |
| SCHEMBL2628952 | 0.71 | CYP2C9 (0.47) | ALDH1A1NR4A2MEN1KMT2ACYP2C9 | |
| Potassium Ion SCHEMBL1763584 | 0.70 | CYP2C9 (0.43) | ALDH1A1NR4A2MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363705-B9 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-1363705-B1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2012-06-13 | — | — | EP | disclosed |