Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.66 |
| ▸ | SHBG | P04278 | 6/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.66 |
| ▸ | TSHR | P16473 | 6/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.66 |
| ▸ | SNCA | P37840 | 4/20 | 0.66 |
| ▸ | BLM | P54132 | 3/20 | 0.66 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.65 |
| ▸ | PGR | P06401 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | AR | P10275 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943275 | 1.00 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL930379 | 0.88 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL930380 | 0.88 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL17301638 | 0.86 | SMN1; SMN2 (0.82) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL17368655 | 0.86 | SMN1; SMN2 (0.82) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL14193763 | 0.86 | SMN1; SMN2 (0.82) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL1041811 | 0.86 | CYP19A1 (0.62) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL13327486 | 0.86 | SMN1; SMN2 (0.70) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL22476664 | 0.84 | CYP19A1 (0.77) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG | |
| SCHEMBL22704745 | 0.84 | CYP19A1 (0.77) | SMN1; SMN2LMNAALDH1A1HSD17B10SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297177-B1 | C-RING-SUBSTITUTED PREGN-4-ENE-21,17-CARBOLACTONE, AND PHARMACEUTICAL PREPARATIONS COMPRISING THE LATTER | Bayer Pharma AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| EP-0402963-A2 | 17-Alpha ethynyl steroids | THE UPJOHN COMPANY (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4614621-A | Ethynylation of 16-methylene-17-keto steroids | THE UPJOHN COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0179496-A1 | 16-Sulfinylmethyl-steroids, their preparation and use | THE UPJOHN COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4567001-A | 16-Methylene-17α-hydroxy-progesterones | THE UPJOHN COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0148616-A2 | Stabilised monolithium acetylide and the ethynylation of steroids | THE UPJOHN COMPANY (US) | 1985-07-17 | — | — | EP | disclosed |
| US-4526720-A | Process to prepare stabilized monolithium acetylide | THE UPJOHN COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0104054-A2 | 16-methylene-steroids and their preparation | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |