Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MC5R | P33032 | 5/20 | 0.44 |
| ▸ | MC3R | P41968 | 4/20 | 0.44 |
| ▸ | MC4R | P32245 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943291 | 0.92 | SOS1 (0.45) | HPGDHTTRECQLMEN1KMT2A | |
| SCHEMBL9943298 | 0.92 | SOS1 (0.45) | HPGDHTTRECQLMEN1KMT2A | |
| SCHEMBL9943392 | 0.89 | HPGD (0.47) | HPGDHTTRECQLMEN1KMT2A | |
| SCHEMBL9943325 | 0.86 | HPGD (0.44) | HPGDHTTRECQLMEN1KMT2A | |
| SCHEMBL9943282 | 0.84 | MC5R (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7256847 | 0.84 | MC4R (0.43) | HPGDHTTRECQLMEN1KMT2A | |
| SCHEMBL9943336 | 0.83 | MC5R (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL9943307 | 0.82 | MC5R (0.48) | SMN1; SMN2MC5RMC3RMC4RCDK4 | |
| SCHEMBL2788385 | 0.81 | CDK4 (0.44) | MAPTMC5RMC3RMC4RHDAC3 | |
| SCHEMBL7251520 | 0.80 | KMT2A (0.46) | HPGDHTTRECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | claimed |
| EP-2099815-B1 | NOVEL AMIDES ACTING ON THE ADENOSINE RECEPTORS | ANAMAR AB (SE) | 2012-06-20 | — | — | EP | disclosed |