SCHEMBL9943510

SCHEMBL9943510

COC(=O)C[C@@H]1C[C@@H](O)CC(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.41
MIF P14174 4/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10041024 0.77 HMGCR (0.43)
SCHEMBL13768714 0.77 HMGCR (0.43)
SCHEMBL8584608 0.76 CYP1A2 (0.45) BRD4MIFHDAC6
SCHEMBL10192955 0.74 PPARG (0.41)
SCHEMBL4651470 0.74 PPARG (0.41)
SCHEMBL18270581 0.74 PPARG (0.41)
SCHEMBL16253816 0.74 PPARG (0.41)
SCHEMBL14454532 0.74 MIF (0.36) BRD4MIFHDAC6
SCHEMBL10324914 0.73 HMGCR (0.40)
SCHEMBL9943440 0.73 HMGCR (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2465936-A1 Enzymatic synthesis of statins and intermediates thereof LEK Pharmaceuticals d.d. (SI) 2012-06-20 EP disclosed