Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | ACR | P10323 | 1/20 | 0.45 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464842 | 0.90 | KMT2A (0.65) | PARP10KMT2AATMMEN1MAPT | |
| SCHEMBL2834801 | 0.86 | PARP10 (0.59) | PARP10KMT2AATMMEN1MAPT | |
| SCHEMBL11125622 | 0.85 | KMT2A (0.59) | PARP10KMT2AATMMEN1MAPT | |
| SCHEMBL29009176 | 0.84 | KMT2A (0.61) | PARP10KMT2AATMMEN1MAPT | |
| SCHEMBL2838573 | 0.84 | KMT2A (0.61) | PARP10KMT2AATMMEN1MAPT | |
| SCHEMBL10794582 | 0.83 | PARP10 (0.57) | PARP10KMT2AATMMEN1MAPT | |
| SCHEMBL9663679 | 0.82 | PARP10 (0.81) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11124086 | 0.81 | BCL2L1 (0.55) | PARP10KMT2AATMMEN1MAPT | |
| SCHEMBL8205435 | 0.80 | PARP10 (0.78) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL725405 | 0.80 | PARP10 (0.77) | PARP10KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465847-B1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2016-10-12 | — | — | EP | disclosed |
| EP-2465847-A1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2012-06-20 | — | — | EP | disclosed |