Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 11/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 7/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 9/20 | 0.49 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.48 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056840 | 0.87 | P2RY2 (0.61) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL18841401 | 0.81 | P2RY2 (0.63) | P2RY2P2RY14P2RY4P2RY6SLC28A1 | |
| SCHEMBL26486106 | 0.79 | P2RY14 (0.75) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL901383 | 0.75 | P2RY2 (0.76) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL9943994 | 0.74 | P2RY6 (0.79) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL12660931 | 0.74 | P2RY2 (0.72) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL28651565 | 0.74 | P2RY2 (0.56) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL28640858 | 0.74 | P2RY14 (0.54) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL12636149 | 0.73 | P2RY2 (0.75) | P2RY2P2RY14P2RY4P2RY6 | |
| SCHEMBL336760 | 0.72 | SLC28A1 (0.69) | P2RY2P2RY14P2RY4P2RY6SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464337-A1 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-20 | — | — | EP | disclosed |