Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 4/20 | 0.61 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.61 |
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CDA | P32320 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.43 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565904 | 0.93 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL7267465 | 0.93 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL27878674 | 0.93 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL565905 | 0.93 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL14853856 | 0.93 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL16805383 | 0.93 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL18852530 | 0.93 | P2RY6 (0.70) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL7527325 | 0.92 | P2RY6 (0.69) | P2RY6P2RY14NT5EABL1RIN1 | |
| Phosphoric Acid SCHEMBL21465041 | 0.90 | P2RY6 (0.72) | P2RY6P2RY14NT5EABL1RIN1 | |
| SCHEMBL432298 | 0.89 | P2RY6 (0.61) | P2RY6P2RY14NT5EABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149888-A1 | SYNTHESIS OF ARA-2'-O-METHYL-NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND OLIGONUCLEOTIDES INCORPORATING NOVEL MODIFICATIONS FOR BIOLOGICAL APPLICATION IN THERAPEUCTICS, DIAGNOSTICS, G- TETRAD FORMING OLIGONUCLEOTIDES AND APTAMERS | CHEMGENES CORPORATION | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149888-A1 | SYNTHESIS OF ARA-2'-O-METHYL-NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND OLIGONUCLEOTIDES INCORPORATING NOVEL MODIFICATIONS FOR BIOLOGICAL APPLICATION IN THERAPEUCTICS, DIAGNOSTICS, G- TETRAD FORMING OLIGONUCLEOTIDES AND APTAMERS | TYMP, MTAP, GART | P2RY6 1387/4885P2RY14 274/4885NT5E 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.