Auriclosene

Auriclosene

SCHEMBL994601

CC(C)(CS(=O)(=O)O)N(Cl)Cl

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Auriclosene SCHEMBL1537304 0.98
Auriclosene SCHEMBL2321981 0.84
SCHEMBL2866753 0.83
SCHEMBL3379316 0.83 CYP1A2 (0.32)
SCHEMBL2870636 0.82 PTGS1 (0.31)
Tetrabuthylammonium SCHEMBL4167461 0.82 SLC22A1 (0.40)
Auriclosene SCHEMBL1537297 0.82 TP53 (0.30)
SCHEMBL20893589 0.81
SCHEMBL27271998 0.78
SCHEMBL2871032 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712436-B2 Theranostic test for antifungal treatment of inflammatory diseases CORNELL UNIVERSITY (US) 2023-08-01 US claimed
CN-116133657-A New compositions and methods for treating covd-19 disease 4活性生物科技公司 2023-05-16 CN claimed
US-20170360880-A1 ANTI-AIDS COCKTAIL CONSISTING OF AN ANTI-TUMORAL COMPOUND, A P-GLYCOPROTEIN INHIBITOR, AND AN ANTI-VIRAL AGENT ARION TECNOLOGIA BRAZIL - GESTÄO DE ATIVOS S/A (BR) 2017-12-21 US claimed
US-20140227201-A1 Antimicrobial Gel Formulations NOVABAY PHARMACEUTICALS, INC. 2014-08-14 US claimed
EP-2531026-A1 POLYSACCHARIDE BASED ANTIMICROBIAL FORMULATIONS NovaBay Pharmaceuticals, Inc. (US) 2012-12-12 EP claimed
US-20120282351-A1 System and Method for The Prevention of Bacterial and Fungal Infections Including Urinary Tract Infections (UTI) Using N-Halogenated Amino Acids NOVABAY PHARMACEUTICALS, INC. 2012-11-08 US claimed
WO-2011097324-A1 POLYSACCHARIDE BASED ANTIMICROBIAL FORMULATIONS NOVABAY PHARMACEUTICALS, INC. (US) 2011-08-11 WO claimed
US-20110190392-A1 Polysaccharide Based Antimicrobial Formulations NOVABAY PHARMACEUTICALS, INC. 2011-08-04 US claimed
US-20110151025-A1 Compositions Comprising N-Halogenated or N,N-Dihalogenated Amine for Treatment and Prophylaxis of Bronchopulmonary Infections NOVABAY PHARMACEUTICALS, INC. 2011-06-23 US claimed
US-20110091570-A1 Compositions and Devices for Antisepsis and Anticoagulation GOTTARDI WALDEMAR 2011-04-21 US claimed
EP-1896001-A1 N-HALOGENATED AMINO ACIDS AND N, N-DIHALOGENATED AMINO ACIDS IN COMBINATION WITH HYPOHALOUS ACIDS Novabay Pharmaceuticals, Inc. (US) 2008-03-12 EP claimed
US-20070292489-A1 METHOD FOR TREATMENT OF WOUND TREATMENT USING AGANOCIDES NOVABAY PHARMACEUTICALS, INC. 2007-12-20 US claimed
EP-1656095-A4 N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES NOVACAL PHARMACEUTICALS INC (US) 2007-11-28 EP claimed
US-20070244449-A1 System and method for the prevention of bacterial and fungal infections including Urinary Tract Infections (UTI) using N-halogenated amino acids NOVACAL PHARMACEUTICALS, INC. 2007-10-18 US claimed
WO-2007044559-A1 SYSTEM AND METHOD FOR THE PREVENTION OF BACTERIAL AND FUNGAL INFECTIONS INCLUDING URINARY TRACT INFECTIONS (UTI) USING N-HALOGENATED AMINO ACIDS NOVABAY PHARMACEUTICALS, INC. (US) 2007-04-19 WO claimed
US-20060247209-A1 N-halogenated amino acids, N,N-dihalogenated amino acids and derivatives; compositions and methods of using them NOVABAY PHARMACEUTICALS, INC. 2006-11-02 US claimed
WO-2006081392-A1 N-HALOGENATED AMINO ACIDS AND N, N-DIHALOGENATED AMINO ACIDS IN COMBINATION WITH HYPOHALOUS ACIDS NOVABAY PHARMACEUTICALS, INC. (US) 2006-08-03 WO claimed
EP-1656095-A2 N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES NovaCal Pharmaceuticals, Inc. (US) 2006-05-17 EP claimed
US-20050065115-A1 N,N-dihalogenated amino acids and derivatives NOVABAY PHARMACEUTICALS, INC. 2005-03-24 US claimed
WO-2005020896-A2 N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES NOVACAL PHARMACEUTICALS, INC. (US) 2005-03-10 WO claimed