Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 18/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307420 | 0.89 | CETP (0.62) | CETPNR1I2KCNH2 | |
| SCHEMBL9946555 | 0.86 | CETP (0.56) | CETPNR1I2KCNH2PTGDR2 | |
| SCHEMBL9946534 | 0.84 | CETP (0.62) | CETPNR1I2 | |
| SCHEMBL4317579 | 0.81 | CETP (0.59) | CETPNR1I2KCNH2PTGDR2 | |
| SCHEMBL4307436 | 0.81 | CETP (0.45) | CETPNR1I2KCNH2PTGDR2 | |
| SCHEMBL4314403 | 0.79 | CETP (0.50) | CETPNR1I2KCNH2 | |
| SCHEMBL4313907 | 0.77 | CETP (0.76) | CETPNR1I2 | |
| SCHEMBL13970553 | 0.76 | CETP (0.46) | CETPNR1I2KCNH2 | |
| SCHEMBL4310656 | 0.76 | CETP (0.78) | CETPKCNH2 | |
| SCHEMBL13950193 | 0.76 | CETP (0.69) | CETPNR1I2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973546-B1 | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS | MERCK SHARP & DOHME (US) | 2012-06-13 | — | — | EP | disclosed |