Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946573 | 0.97 | HDAC1 (0.38) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL9895162 | 0.89 | HDAC3 (0.39) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL7896386 | 0.89 | HDAC3 (0.39) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL7897506 | 0.85 | SMN1; SMN2 (0.38) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL9895879 | 0.85 | SMN1; SMN2 (0.38) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL7897997 | 0.84 | HDAC3 (0.56) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL9895603 | 0.84 | HDAC3 (0.56) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL7898196 | 0.82 | HDAC3 (0.54) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL9895471 | 0.82 | HDAC3 (0.54) | HDAC1HDAC3HDAC8HDAC6HDAC4 | |
| SCHEMBL10072240 | 0.82 | SMN1; SMN2 (0.36) | HDAC1HDAC3HDAC8HDAC6HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149736-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149736-A1 | ENZYME INHIBITORS | HAT1, HDAC1, NAT1 | HDAC1 2/4885HDAC3 5/4885HDAC8 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.