SCHEMBL9946967

SCHEMBL9946967

CN(C)CC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3372253 0.96
SCHEMBL27362046 0.81
SCHEMBL90097 0.77
SCHEMBL1338798 0.74
SCHEMBL22928626 0.74
SCHEMBL20284338 0.72
SCHEMBL16295833 0.72
SCHEMBL27660083 0.72
SCHEMBL2228359 0.72
SCHEMBL18231836 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289822-A2 BENZOIMIDAZOL-1,2-YL AMIDES AS KV7 CHANNEL ACTIVATORS Biohaven Therapeutics Ltd. (US) 2023-12-13 EP disclosed
WO-2023215367-A1 BICYCLIC PIPERAZINONES AND THERAPEUTIC USES THEREOF CYTOKINETICS, INC. (US) 2023-11-09 WO disclosed
US-20230348779-A1 FLUORESCENT COMPOUND AND FLUORESCENTLY LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-11-02 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230286975-A1 IMPROVED METHOD FOR THE PRODUCTION OF LYSERGIC ACID DIETHYLAMIDE (LSD) AND NOVEL DERIVATIVES THEREOF MIHKAL GMBH (CH) 2023-09-14 US disclosed
US-20230286975-A1 IMPROVED METHOD FOR THE PRODUCTION OF LYSERGIC ACID DIETHYLAMIDE (LSD) AND NOVEL DERIVATIVES THEREOF MIHKAL GMBH (CH) 2023-09-14 US disclosed
EP-3743430-B1 AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2023-08-02 EP disclosed
US-20230141101-A1 PDE4 INHIBITOR COMPOUND AND MEDICAL USE THEREOF SUZHOU LONGBOTAI PHARMACEUTICALS CO., LTD. (CN) 2023-05-11 US disclosed
US-20230141101-A1 PDE4 INHIBITOR COMPOUND AND MEDICAL USE THEREOF SUZHOU LONGBOTAI PHARMACEUTICALS CO., LTD. (CN) 2023-05-11 US disclosed
US-20120270882-A1 FLUORINATED DERIVATES OF 3-HYDROXYPYRIDIN-4-ONES APOTEX TECHNOLOGIES INC. (CA) 2012-10-25 US disclosed
EP-2484661-A1 2,3-DIHYDRO-1H-INDENE-2-YLUREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME Toray Industries, Inc. (JP) 2012-08-08 EP disclosed
US-20120184735-A1 2,3-DIHYDRO-1H-INDENE-2-YL UREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME TORAY INDUSTRIES, INC. (JP) 2012-07-19 US disclosed
WO-2012076673-A1 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-06-14 WO disclosed
WO-2012001107-A1 PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-01-05 WO disclosed
WO-2010131145-A1 CYCLOBUTENEDIONE DERIVATIVES PFIZER LIMITED (GB) 2010-11-18 WO disclosed
US-7250429-B2 Aminomethyl-substituted thiazolobenzimidazole compounds ASTELLAS PHARMA INC. (JP) 2007-07-31 US disclosed
US-7157454-B2 Derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and the pharmaceutical compositions containing same SANOFI-AVENTIS (FR) 2007-01-02 US disclosed
US-4585569-A FLUOROALKYLAMINE AS WORKING FLUID IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-29 US disclosed
EP-0155423-A2 Heat pumps IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-25 EP disclosed