Propionyl-Carnitine

Propionyl-Carnitine

SCHEMBL994714

CCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C.CCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
CYP2C19 P33261 2/20 1.00
RECQL P46063 1/20 1.00
CYP1A2 P05177 4/20 0.69
HRH1 P35367 1/20 0.69
SLC25A20 O43772 3/20 0.68
TP53 P04637 3/20 0.68
TSHR P16473 3/20 0.68
MAPT P10636 3/20 0.68
CYP2D6 P10635 2/20 0.68
SLC6A5 Q9Y345 2/20 0.68
CYP2C9 P11712 2/20 0.68
HIF1A Q16665 2/20 0.68
KDM4E B2RXH2 1/20 0.68
CYP3A4 P08684 1/20 0.68
NFKB1 P19838 1/20 0.68
THPO P40225 1/20 0.68
HSD17B10 Q99714 1/20 0.68
CPT2 P23786 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionyl-Carnitine SCHEMBL156850 1.00 MEN1 (1.00) MEN1KMT2ACYP2C19RECQLCYP1A2
Levocarnitine Propionate SCHEMBL464940 1.00 MEN1 (1.00) MEN1KMT2ACYP2C19RECQLCYP1A2
Levocarnitine Propionate SCHEMBL1358528 0.98 MEN1 (0.97) MEN1KMT2ACYP2C19RECQLCYP1A2
Levocarnitine Propionate SCHEMBL3005249 0.98 MEN1 (0.97) MEN1KMT2ACYP2C19RECQLCYP1A2
Propionyl-Carnitine SCHEMBL1358526 0.98 MEN1 (0.97) MEN1KMT2ACYP2C19RECQLCYP1A2
Propionyl-Carnitine SCHEMBL19617435 0.95 MEN1 (0.90) MEN1KMT2ACYP2C19RECQLCYP1A2
Propionyl-Carnitine SCHEMBL583770 0.94 MEN1 (0.88) MEN1KMT2ACYP2C19RECQLCYP1A2
Propionyl-Carnitine SCHEMBL16781736 0.92 MEN1 (0.85) MEN1KMT2ACYP2C19RECQLCYP1A2
Propionyl-Carnitine SCHEMBL527837 0.92 MEN1 (0.85) MEN1KMT2ACYP2C19RECQLCYP1A2
Levocarnitine Propionate SCHEMBL16781737 0.92 MEN1 (0.85) MEN1KMT2ACYP2C19RECQLCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2449488-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES Life Sciences AG (AT) 2012-05-09 EP disclosed
WO-2011000753-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES LIFE SCIENCES AG (AT) 2011-01-06 WO disclosed