Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567047 | 1.00 | PIK3CD (0.47) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9947450 | 0.98 | PIK3CD (0.45) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9947438 | 0.98 | PIK3CD (0.49) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL15472252 | 0.98 | PIK3CD (0.49) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL8544853 | 0.98 | PIK3CD (0.45) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9947458 | 0.98 | PIK3CD (0.45) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9947457 | 0.97 | PIK3CD (0.46) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL9947467 | 0.95 | PIK3CD (0.51) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL8524177 | 0.85 | PIK3CD (0.45) | PIK3CDCHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL8544980 | 0.80 | PIK3CD (0.49) | PIK3CDCHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9993559-B2 | N-alkyl lactam ethers, and compositions and uses thereof | ISP INVESTMENTS LLC (US) | 2018-06-12 | — | — | US | disclosed |
| US-20160271254-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-9351484-B2 | N-alkyl lactam ethers, and compositions and uses thereof | ISP INVESTMENTS INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140045698-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2014-02-13 | — | — | US | disclosed |
| US-20120148514-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271254-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | USP8, MLST8, CYP2C8 | PIK3CD 357/4885CHRM2 2369/4885CHRM5 2653/4885 |
| US-20140045698-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | USP8, MLST8, CYP2C8 | PIK3CD 357/4885CHRM2 2369/4885CHRM5 2653/4885 |
| US-20120148514-A1 | N-ALKYL LACTAM ETHERS, AND COMPOSITIONS AND USES THEREOF | USP8, MLST8, CYP2C8 | PIK3CD 357/4885CHRM2 2369/4885CHRM5 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.