Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.65 |
| ▸ | GSK3B | P49841 | 4/20 | 0.65 |
| ▸ | BACE1 | P56817 | 3/20 | 0.65 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.58 |
| ▸ | STAT3 | P40763 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020459 | 1.00 | HDAC1 (0.65) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15020457 | 1.00 | HDAC1 (0.65) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL29924064 | 1.00 | HDAC1 (0.65) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL31682437 | 1.00 | HDAC1 (0.65) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL9947558 | 0.94 | HDAC1 (0.72) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL10050481 | 0.91 | GSK3B (0.58) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL15042798 | 0.91 | HDAC1 (0.60) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL9947551 | 0.87 | HDAC1 (0.61) | HDAC1HDAC2HDAC8GSK3BNFKB1 | |
| SCHEMBL12336501 | 0.87 | APP (0.72) | HDAC1HDAC2HDAC8GSK3BBACE1 | |
| SCHEMBL13125804 | 0.87 | APP (0.72) | HDAC1HDAC2HDAC8GSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076696-A1 | NEW METAL CARBONYL COMPLEXES OF CURCUMIN DERIVATIVES, THEIR SYNTHESIS AND THEIR USES IN THERAPEUTIC APPLICATION | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2012-06-14 | — | — | WO | disclosed |