Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 19/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 15/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994812 | 0.98 | NR1H2 (0.51) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL994166 | 0.94 | NR1H2 (0.53) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL994844 | 0.94 | NR1H2 (0.52) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL994593 | 0.92 | NR1H2 (0.49) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL995201 | 0.92 | NR1H2 (0.51) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL12392225 | 0.92 | NR1H2 (0.46) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL3171339 | 0.91 | NR1H2 (0.50) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL2350388 | 0.91 | NR1H2 (0.48) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL997377 | 0.90 | NR1H2 (0.47) | NR1H2NR1H3PPARGPPARDPPARA | |
| SCHEMBL12392215 | 0.90 | NR1H2 (0.43) | NR1H2NR1H3PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272843-A1 | QUINOLINE COMPOUND | Kowa Company, Ltd. (JP) | 2011-01-12 | — | — | EP | disclosed |