⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402057 | 0.68 | — | — | |
| SCHEMBL22181784 | 0.57 | — | — | |
| SCHEMBL11263459 | 0.54 | — | — | |
| SCHEMBL14398442 | 0.54 | PTPN22 (0.37) | — | |
| SCHEMBL5607077 | 0.54 | — | — | |
| SCHEMBL6603955 | 0.54 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL11133453 | 0.54 | BACE1 (0.41) | — | |
| SCHEMBL23233734 | 0.54 | — | — | |
| SCHEMBL12962901 | 0.54 | — | — | |
| SCHEMBL10031673 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4578500-A2 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODEGENERATIVE DISEASES AND COGNITIVE DISORDERS | Amazentis SA (CH) | 2025-07-02 | — | — | EP | disclosed |
| US-12310943-B2 | Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders | AMAZENTIS SA (CH) | 2025-05-27 | — | — | US | disclosed |
| EP-3372228-B1 | NON-THERAPEUTIC METHOD OF INCREASING OR MAINTAINING MITOCHONDRIAL FUNCTION | AMAZENTIS SA (CH) | 2025-03-12 | — | — | EP | disclosed |
| EP-3369420-B1 | NON-THERAPEUTIC USE OF UROLITHIN A FOR IMPROVING COGNITIVE FUNCTION. | AMAZENTIS SA (CH) | 2025-03-12 | — | — | EP | disclosed |
| US-12036205-B2 | Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders | AMAZENTIS SA (CH) | 2024-07-16 | — | — | US | disclosed |
| US-20240156777-A1 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODEGENERATIVE DISEASES AND COGNITIVE DISORDERS | AMAZENTIS SA (CH) | 2024-05-16 | — | — | US | disclosed |
| US-20240100016-A1 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODEGENERATIVE DISEASES AND COGNITIVE DISORDERS | AMAZENTIS SA (CH) | 2024-03-28 | — | — | US | disclosed |
| US-11903922-B2 | Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders | AMAZENTIS SA (CH) | 2024-02-20 | — | — | US | disclosed |
| US-20220280475-A1 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODEGENERATIVE DISEASES AND COGNITIVE DISORDERS | AMAZENTIS SA (CH) | 2022-09-08 | — | — | US | disclosed |
| US-11234960-B2 | Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders | AMAZENTIS SA (CH) | 2022-02-01 | — | — | US | disclosed |
| EP-2654461-B1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS | AMAZENTIS SA (CH) | 2018-04-11 | — | — | EP | disclosed |
| EP-3278800-A2 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING MUSCLE-RELATED PATHOLOGICAL CONDITIONS | Amazentis SA (CH) | 2018-02-07 | — | — | EP | disclosed |
| US-9872850-B2 | Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders | AMAZENTIS SA (CH) | 2018-01-23 | — | — | US | disclosed |
| US-20170143667-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | AMAZENTIS SA (CH) | 2017-05-25 | — | — | US | disclosed |
| US-20170143666-A1 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODEGENERATIVE DISEASES AND COGNITIVE DISORDERS | AMAZENTIS SA (CH) | 2017-05-25 | — | — | US | disclosed |
| US-20160213643-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | AMAZENTIS SA (CH) | 2016-07-28 | — | — | US | disclosed |
| US-20160213641-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-07-28 | — | — | US | disclosed |
| EP-2654461-A2 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODENEGENERATIVE DISEASES AND COGNITIVE DISORDERS | Amazentis SA (CH) | 2013-10-30 | — | — | EP | disclosed |
| US-20120164243-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | AMAZENTIS SA (CH) | 2012-06-28 | — | — | US | disclosed |
| WO-2012088519-A2 | COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODENEGENERATIVE DISEASES AND COGNITIVE DISORDERS | AMAZENTIS SA (CH) | 2012-06-28 | — | — | WO | disclosed |