Glutamine

Glutamine

SCHEMBL994966

NC(=O)CCC(N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
ALOX15 P16050 1/20 1.00
BLM P54132 1/20 1.00
PMP22 Q01453 1/20 1.00
GSR P00390 2/20 0.68
CYP1A2 P05177 2/20 0.68
GRM8 O00222 2/20 0.68
GRM6 O15303 2/20 0.68
GRM7 Q14831 2/20 0.68
GRM4 Q14833 2/20 0.68
GRIN2D O15399 1/20 0.68
GRIN3B O60391 1/20 0.68
GRIK1 P39086 1/20 0.68
GRM5 P41594 1/20 0.68
GRIA1 P42261 1/20 0.68
GRIA2 P42262 1/20 0.68
GRIA3 P42263 1/20 0.68
SLC1A3 P43003 1/20 0.68
SLC1A2 P43004 1/20 0.68
SLC1A1 P43005 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL31436292 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL711605 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL7452 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL411575 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL411170 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL5580393 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL7453 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL411588 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL1332116 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL31619675 1.00 KMT2A (1.00) KMT2AALOX15BLMPMP22GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8790897-B2 Treatment of mucus hypersecretion SYNTAXIN LTD. (GB) 2014-07-29 US disclosed
EP-2449488-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES Life Sciences AG (AT) 2012-05-09 EP disclosed
US-7882838-B2 Exothermic condom packaging BLAISE HARRISON, LLC (US) 2011-02-08 US disclosed
WO-2011000753-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES LIFE SCIENCES AG (AT) 2011-01-06 WO disclosed
US-20080249019-A1 TREATMENT OF MUCUS HYPERSECRETION SYNTAXIN, LTD. (GB) 2008-10-09 US disclosed
US-7358241-B2 Compositions and methods comprising farnesyl dibenzodiazepinones for treating neoplastic cells and conditions THALLION PHARMACEUTICALS, INC. (CA) 2008-04-15 US disclosed
US-20080032928-A1 Treatment of mucus hypersecretion SYNTAXIN LTD. 2008-02-07 US disclosed
US-20060079508-A1 Compositions and methods comprising farnesyl dibenzodiazepinones for treating neoplastic cells and conditions ECOPIA BIOSCIENCES, INC. 2006-04-13 US disclosed
US-20020137189-A1 Cardiac hypertrophy factor and uses therefor GENENTECH, INC. 2002-09-26 US disclosed
US-5668253-A POLYPEPTIDES AS ANTIGENS AND ANTIBODIES HEALTH RESEARCH, INC. (US) 1997-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060079508-A1 Compositions and methods comprising farnesyl dibenzodiazepinones for treating neoplastic cells and conditions KRAS, MCL1, FNTB KMT2A 3981/4885ALOX15 125/4885BLM 557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.