Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 14/20 | 0.59 |
| ▸ | CDK9 | P50750 | 7/20 | 0.49 |
| ▸ | CCNK | O75909 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9949688 | 1.00 | CCNT1 (0.59) | CCNT1CDK9CCNK | |
| SCHEMBL9949440 | 0.93 | CCNT1 (0.62) | CCNT1CDK9CCNK | |
| SCHEMBL9949436 | 0.93 | CCNT1 (0.62) | CCNT1CDK9CCNK | |
| SCHEMBL1441057 | 0.91 | CCNT1 (0.60) | CCNT1CDK9CCNK | |
| SCHEMBL1439560 | 0.91 | CCNT1 (0.60) | CCNT1CDK9CCNK | |
| SCHEMBL1439981 | 0.91 | CCNT1 (0.60) | CCNT1CDK9CCNK | |
| SCHEMBL10285389 | 0.90 | CCNT1 (0.64) | CCNT1CDK9CCNK | |
| SCHEMBL10285382 | 0.90 | CCNT1 (0.64) | CCNT1CDK9CCNK | |
| SCHEMBL1439549 | 0.90 | CCNT1 (0.64) | CCNT1CDK9CCNK | |
| SCHEMBL1439911 | 0.88 | CCNT1 (0.60) | CCNT1CDK9CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165306-A1 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165306-A1 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | CDK4, CDK1, CCNI | CCNT1 39/4885CDK9 16/4885CCNK 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.