Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 9/20 | 0.44 |
| ▸ | CCNK | O75909 | 7/20 | 0.43 |
| ▸ | CDK9 | P50750 | 7/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9950176 | 0.83 | PIM1 (0.43) | CCNT1CCNKCDK9PIM1PIM2 | |
| SCHEMBL9950510 | 0.80 | CCNT1 (0.50) | CCNT1PIM2ALDH1A1CYP1A2CLK4 | |
| SCHEMBL9949642 | 0.78 | SMN1; SMN2 (0.45) | CCNT1ALDH1A1 | |
| SCHEMBL9950123 | 0.78 | SMN1; SMN2 (0.45) | CCNT1ALDH1A1 | |
| SCHEMBL9949608 | 0.77 | CCNT1 (0.60) | CCNT1CCNKCDK9PIM1PIM2 | |
| SCHEMBL9950496 | 0.74 | CCNT1 (0.63) | CCNT1ALDH1A1 | |
| SCHEMBL9949998 | 0.74 | CCNT1 (0.63) | CCNT1 | |
| SCHEMBL31492959 | 0.74 | HRH1 (0.44) | CDK9PIM1PIM2ALDH1A1CYP1A2 | |
| SCHEMBL9949473 | 0.73 | CCNT1 (0.51) | CCNT1 | |
| SCHEMBL9949452 | 0.73 | CCNT1 (0.59) | CCNT1CDK9CYP1A2CYP2C19CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165306-A1 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165306-A1 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | CDK4, CDK1, CCNI | CCNT1 39/4885CCNK 23/4885CDK9 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.