SCHEMBL9950862

SCHEMBL9950862

COc1ccc2ccccc2c1-c1ccccc1F

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.68
KMT2A Q03164 5/20 0.55
MEN1 O00255 4/20 0.55
ALDH1A1 P00352 2/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
NISCH Q9Y2I1 1/20 0.49
KDM4E B2RXH2 2/20 0.44
USP2 O75604 1/20 0.44
DUSP3 P51452 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NQO1 P15559 1/20 0.43
HPGD P15428 1/20 0.43
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.42
RPS6KA2 Q15349 2/20 0.42
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
ERN1 O75460 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31010719 0.85 MAPT (0.66) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL22658238 0.85 MAPT (0.66) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL28881056 0.84 MAPT (0.51) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL29512056 0.84 MAPT (0.75) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL12880138 0.84 MAPT (0.75) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL23581961 0.83 MAPT (0.73) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL29467232 0.83 MAPT (0.73) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL22127108 0.83 MAPT (0.58) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL24583337 0.82 MAPT (0.57) MAPTKMT2AMEN1ALDH1A1RAB9A
SCHEMBL31010724 0.82 MAPT (0.57) MAPTKMT2AMEN1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103339120-B Benzo [b] naphtho-[1,2-d] furan compound as light emitting element material 株式会社半导体能源研究所 2016-08-10 CN disclosed
US-8674117-B2 Organoboron compound and method for manufacturing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
US-8674117-B2 Organoboron compound and method for manufacturing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
US-8674117-B2 Organoboron compound and method for manufacturing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
US-8604224-B2 Benzo[b]naphtho[1,2-d]furan compound as light-emitting element material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-12-10 US disclosed
CN-103339120-A Benzo[b]naphtho[1,2-d]furan compound as light-emitting element material SEMINCONDUCTOR ENERGY LAB CO 2013-10-02 CN disclosed
WO-2012090888-A1 ORGANOBORON COMPOUND AND METHOD FOR MANUFACTURING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-05 WO disclosed
WO-2012090970-A1 BENZO[b]NAPHTHO[1,2-d]FURAN COMPOUND AS LIGHT-EMITTING ELEMENT MATERIAL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-05 WO disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165550-A1 Organoboron Compound and Method for Manufacturing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165550-A1 Organoboron Compound and Method for Manufacturing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165550-A1 Organoboron Compound and Method for Manufacturing the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165550-A1 Organoboron Compound and Method for Manufacturing the Same CYP2B6, CBR3, CBR1 MAPT 3496/4885KMT2A 4513/4885MEN1 1969/4885
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 MAPT 3998/4885KMT2A 3200/4885MEN1 1235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.