Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948052 | 0.82 | BACE1 (0.74) | BACE1APP | |
| SCHEMBL9948524 | 0.80 | BACE1 (0.67) | BACE1APP | |
| SCHEMBL9948652 | 0.77 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948073 | 0.75 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948109 | 0.75 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948389 | 0.74 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948418 | 0.73 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948402 | 0.72 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL9948075 | 0.72 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL28808064 | 0.71 | BACE1 (0.73) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655378-A1 | COMPOUNDS AND THEIR USE AS BACE INHIBITORS | AstraZeneca AB (SE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087237-A1 | COMPOUNDS AND THEIR USE AS BACE INHIBITORS | ASTRAZENECA AB (SE) | 2012-06-28 | — | — | WO | disclosed |