Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070914 | 0.98 | POLB (0.44) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL1447226 | 0.90 | — | — | |
| SCHEMBL14739265 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL14740296 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL14740248 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL14739086 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL14739816 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL14740061 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL14739515 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA | |
| SCHEMBL15836237 | 0.87 | GRIA1 (0.52) | GRIA1POLBCA2CA1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655362-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | Abbvie Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087833-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-06-28 | — | — | WO | disclosed |