Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952172 | 0.87 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL9960475 | 0.84 | PIK3CD (0.43) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL9952359 | 0.83 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL9952823 | 0.82 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL9929092 | 0.80 | PIK3CD (0.79) | PIK3CDPIK3CG | |
| SCHEMBL9929185 | 0.80 | PIK3CD (0.64) | PIK3CDPIK3CG | |
| SCHEMBL9953057 | 0.80 | PIK3CD (0.44) | PIK3CDPIK3CG | |
| SCHEMBL12813060 | 0.79 | PIK3CD (0.69) | PIK3CDPIK3CG | |
| SCHEMBL9952453 | 0.78 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL9953808 | 0.77 | PIK3CD (0.38) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |