Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991659 | 0.98 | TDP1 (0.82) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL8198198 | 0.93 | TDP1 (0.68) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL2882808 | 0.93 | TDP1 (0.68) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL8201062 | 0.93 | TDP1 (0.68) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL7933696 | 0.91 | TDP1 (0.70) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL6427937 | 0.91 | TDP1 (0.89) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL21638946 | 0.89 | TDP1 (0.66) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL1582872 | 0.89 | TDP1 (1.00) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL17028904 | 0.89 | TDP1 (1.00) | TDP1ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL1583161 | 0.89 | TDP1 (1.00) | TDP1ALDH1A1TSHRTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655484-B1 | POLYMERIC MATERIALS | COLORMATRIX HOLDINGS INC (US) | 2017-06-14 | — | — | EP | disclosed |
| US-9139704-B2 | Polymeric materials | COLORMATRIX HOLDINGS, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20130338308-A1 | POLYMERIC MATERIALS | Colomatrix Holdings, Inc. (US) | 2013-12-19 | — | — | US | disclosed |
| EP-2655484-A2 | POLYMERIC MATERIALS | Colormatrix Holdings, Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085548-A2 | POLYMERIC MATERIALS | COLORMATRIX HOLDINGS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |