Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953675 | 0.88 | SCN9A (1.00) | SCN9AFPR2 | |
| SCHEMBL9953278 | 0.76 | SCN9A (0.61) | SCN9A | |
| SCHEMBL9953642 | 0.76 | SCN9A (1.00) | SCN9AFPR2 | |
| SCHEMBL9953647 | 0.76 | SCN9A (1.00) | SCN9AFPR2 | |
| SCHEMBL787633 | 0.76 | SCN9A (0.60) | SCN9A | |
| SCHEMBL9953703 | 0.75 | SCN9A (0.64) | SCN9AFPR2 | |
| SCHEMBL9953218 | 0.74 | SCN9A (0.84) | SCN9AFPR2 | |
| SCHEMBL9953216 | 0.74 | SCN9A (0.84) | SCN9AFPR2 | |
| SCHEMBL805905 | 0.73 | SCN9A (0.67) | SCN9AFPR2 | |
| SCHEMBL3143887 | 0.73 | SCN9A (0.61) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656959-B2 | Substituted pyridines as sodium channel blockers | PURDUE PHARMA L.P. (US) | 2017-05-23 | — | — | US | claimed |
| EP-2655330-B1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2016-02-10 | — | — | EP | claimed |
| US-20140005212-A1 | Substituted Pyridines as Sodium Channel Blockers | PURDUE PHARMA L.P. (US) | 2014-01-02 | — | — | US | claimed |
| EP-2655330-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | Purdue Pharma LP (US) | 2013-10-30 | — | — | EP | claimed |
| WO-2012085650-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | claimed |
| US-9656959-B2 | Substituted pyridines as sodium channel blockers | PURDUE PHARMA L.P. (US) | 2017-05-23 | — | — | US | disclosed |
| US-9656959-B2 | Substituted pyridines as sodium channel blockers | PURDUE PHARMA L.P. (US) | 2017-05-23 | — | — | US | disclosed |
| EP-2655330-B1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2016-02-10 | — | — | EP | disclosed |
| EP-2655330-B1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA LP (US) | 2016-02-10 | — | — | EP | disclosed |
| US-20140005212-A1 | Substituted Pyridines as Sodium Channel Blockers | PURDUE PHARMA L.P. (US) | 2014-01-02 | — | — | US | disclosed |
| EP-2655330-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | Purdue Pharma LP (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085650-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012085650-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005212-A1 | Substituted Pyridines as Sodium Channel Blockers | SCN1B, CACNA1A, SCN1A | SCN9A 97/4885FPR2 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.