Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953190 | 0.80 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL9952122 | 0.79 | PIK3CD (0.37) | PIK3CDL3MBTL1 | |
| SCHEMBL9928906 | 0.78 | PIK3CD (0.41) | PIK3CDL3MBTL1 | |
| SCHEMBL9929494 | 0.68 | PIK3CD (0.44) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL9952333 | 0.68 | PIK3CD (0.34) | PIK3CD | |
| Trifluoroacetic Acid SCHEMBL9929245 | 0.67 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL14736118 | 0.67 | PIK3CD (0.49) | PIK3CD | |
| SCHEMBL15996126 | 0.63 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL14736330 | 0.62 | PIK3CD (0.59) | PIK3CD | |
| SCHEMBL14742470 | 0.61 | PIK3CD (0.35) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |