Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 18/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.52 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247746 | 0.90 | ATR (0.46) | PI4KAPIK3CGATRPIK3CDPIK3CA | |
| SCHEMBL9953864 | 0.90 | PI4KA (0.67) | PI4KAPIK3CG | |
| SCHEMBL9954059 | 0.90 | PI4KA (0.64) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9954271 | 0.90 | PI4KA (0.68) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9953283 | 0.88 | PI4KA (0.61) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9953826 | 0.84 | PI4KA (0.67) | PI4KAPIK3CG | |
| SCHEMBL9954130 | 0.83 | PI4KA (0.62) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL14247252 | 0.83 | PIK3CG (0.43) | PI4KAPIK3CGATRPIK3CDPIK3CA | |
| SCHEMBL9960593 | 0.81 | PI4KA (0.62) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9960577 | 0.81 | PI4KA (0.74) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |