Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 6/20 | 0.61 |
| ▸ | CA2 | P00918 | 6/20 | 0.61 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6045363 | 1.00 | NPC1 (0.74) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL7152297 | 1.00 | NPC1 (0.74) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL7151149 | 1.00 | NPC1 (0.74) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL2573474 | 0.98 | NPC1 (0.76) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL14353200 | 0.98 | NPC1 (0.76) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL2573470 | 0.98 | NPC1 (0.76) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL14478652 | 0.98 | NPC1 (0.76) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL7150020 | 0.98 | NPC1 (0.76) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL7152391 | 0.98 | NPC1 (0.76) | NPC1RAB9ATSHRCA1CA2 | |
| SCHEMBL7153084 | 0.98 | NPC1 (0.76) | NPC1RAB9ATSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970860-A1 | GENETICALLY MODIFIED BACTERIA | President and Fellows of Harvard College (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150353961-A1 | Designer Photoautotrophic and Hydrogenotrophic Production of Alcohols and Biodiesel | LEE JAMES WEIFU (US) | 2015-12-10 | — | — | US | disclosed |
| WO-2014158590-A1 | GENETICALLY MODIFIED BACTERIA | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20130344553-A1 | Designer Calvin-Cycle-Channeled and Hydrogenotrophic Production of Butanol and Related Higher Alcohols | LEE JAMES WEIFU (US) | 2013-12-26 | — | — | US | disclosed |
| EP-2655599-A2 | DESIGNER CALVIN-CYCLE-CHANNELED AND HYDROGENOTROPHIC PRODUCTION OF BUTANOL AND RELATED HIGHER ALCOHOLS | Lee, James Weifu (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130217592-A1 | ARRAYS AND METHODS COMPRISING M. SMITHII GENE PRODUCTS | THE WASHINGTON UNIVERSITY (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2012088071-A2 | DESIGNER CALVIN-CYCLE-CHANNELED AND HYDROGENOTROPHIC PRODUCTION OF BUTANOL AND RELATED HIGHER ALCOHOLS | LEE JAMES WEIFU (US) | 2012-06-28 | — | — | WO | disclosed |