Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 14/20 | 0.76 |
| ▸ | PI4KA | P42356 | 14/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.63 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953853 | 0.94 | PI4KA (0.79) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL9958973 | 0.94 | PI4KA (0.78) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL9954455 | 0.94 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL9954378 | 0.93 | PI4KA (0.77) | PIK3CGPI4KAPIK3CAPIK3R1 | |
| SCHEMBL14317328 | 0.92 | PIK3CG (0.62) | PIK3CGPI4KAPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL9954398 | 0.90 | PI4KA (0.81) | PIK3CGPI4KAPIK3CAPIK3CDPIK3R1 | |
| Formic Acid SCHEMBL14247479 | 0.89 | PIK3CG (0.59) | PIK3CGPI4KAPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL9953710 | 0.88 | PI4KA (0.81) | PIK3CGPI4KAPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL9954078 | 0.88 | PI4KA (0.78) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL9953682 | 0.87 | PI4KA (0.93) | PIK3CGPI4KAPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |